Hypothesis: Homologous Recombination Depends on Parallel Search.
نویسنده
چکیده
It is not known how a cell manages to find a specific DNA sequence sufficiently fast to repair a broken chromosome through homologous recombination. I propose a solution based on freely diffusing molecules that are programmed with sequences corresponding to those flanking the break site. In such a process, the target search would be parallelized.
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عنوان ژورنال:
- Cell systems
دوره 3 4 شماره
صفحات -
تاریخ انتشار 2016